Biomarkers
Everything on Aqrab tagged Biomarkers — grouped into one landing page so readers can go deeper by problem family instead of bouncing around the archive blind.
Below the Quantification Limit Is Not Zero: A Biomarker Data Audit
A below-limit biomarker result is not a measured zero. A small example shows why fixed replacement values hide information and what to report before modeling an association.
Batch Effects: When a Biomarker Follows the Plate, Not the Patient
A practical group-by-batch audit shows why a biomarker difference cannot be separated from technical conditions when cases and controls occupy different batches.
Surrogate Endpoints: When a Biomarker Improvement Pretends to Be Patient Benefit
A practical guide to surrogate endpoints for clinical researchers. Covers validated versus merely plausible surrogates, classic failure modes, and what reviewers should demand before trusting a biomarker-driven trial claim.
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These are ranked by how often they appear alongside Biomarkers, so the next click is more likely to be useful than random.